Phenotypes Associated with This Genotype

Genotype
MGI:5285112

• Allelic Composition: Tdg^tm2.1Abc/Tdg^tm2.1Abc
• Genetic Background: B6.129-Tdg^tm2.1Abc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:174772 )

• at E10.5

embryo

abnormal embryo turning ( J:174772 )

embryonic growth retardation ( J:174772 )

decreased embryo size ( J:174772 )

cardiovascular system

pericardial effusion ( J:174772 )

cellular

abnormal DNA methylation ( J:174772 )

• abrogation of methylation at the Tat enhancer

homeostasis/metabolism

pericardial effusion ( J:174772 )

growth/size/body

embryonic growth retardation ( J:174772 )

decreased embryo size ( J:174772 )