Phenotypes for Jun Jund MGI:5284981 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Jun^{tm6.1(Jund)Wag}/Jun^{tm6.1(Jund)Wag} Jund^tm1Mya/Jund^tm1Mya
Genetic Background	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jund^tm1Mya mutation (0 available); any Jund mutation (4 available)
Jun^{tm6.1(Jund)Wag} mutation (0 available); any Jun mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:175212 )

• mice do not develop beyond E13

cellular

decreased fibroblast proliferation ( J:175212 )

• in mouse embryonic fibroblasts

early cellular replicative senescence ( J:175212 )

• in mouse embryonic fibroblasts

embryo

embryonic growth retardation ( J:175212 )

• severe

growth/size/body

embryonic growth retardation ( J:175212 )

• severe

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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