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Phenotypes Associated with This Genotype
Genotype
MGI:5142229
Allelic
Composition		 Agrptm1(cre)Lowl/Agrp+
Leprtm1.1Chua/Leprtm1.1Chua
Tg(Pomc1-hrGFP)1Lowl/0
Genetic
Background		 involves: 129S6/SvEvTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agrptm1(cre)Lowl mutation (1 available); any Agrp mutation (18 available)
Leprtm1.1Chua mutation (1 available); any Lepr mutation (121 available)
Tg(Pomc1-hrGFP)1Lowl mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:174691 )
N
• addition of leptin produces similar inhibition of sIPSCs in neurons to that observed in control preparations

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory