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Phenotypes Associated with This Genotype
Genotype
MGI:5140808
Allelic
Composition		 Bcl6tm1.1Toka/Bcl6+
Tg(TcraTcrb)425Cbn/0
Genetic
Background		 involves: BALB/c * C57BL/6 * NZB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcl6tm1.1Toka mutation (1 available); any Bcl6 mutation (60 available)
Tg(TcraTcrb)425Cbn mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased T cell proliferation ( J:174014 )
• T follicular helper cells in mice immunized with NP-ovalbumin exhibit accelerated proliferatively quiescent unlike wild-type cells

hematopoietic system
decreased T cell proliferation ( J:174014 )
• T follicular helper cells in mice immunized with NP-ovalbumin exhibit accelerated proliferatively quiescent unlike wild-type cells

cellular
decreased T cell proliferation ( J:174014 )
• T follicular helper cells in mice immunized with NP-ovalbumin exhibit accelerated proliferatively quiescent unlike wild-type cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory