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Phenotypes Associated with This Genotype
Genotype
MGI:5140807
Allelic
Composition		 Bcl6tm1.1Toka/Bcl6tm1.1Toka
Genetic
Background		 involves: C57BL/6 * NZB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcl6tm1.1Toka mutation (1 available); any Bcl6 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:174014 )
N
• antibody class switching is normal
abnormal Peyer's patch morphology ( J:174014 )
• Peyer's patches contain fewer T follicular helper cells compared to in wild-type mice

hematopoietic system

digestive/alimentary system
abnormal Peyer's patch morphology ( J:174014 )
• Peyer's patches contain fewer T follicular helper cells compared to in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory