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Phenotypes Associated with This Genotype
Genotype
MGI:5140412
Allelic
Composition		 Ightm1.1Twin/Ightm1.1Twin
Plcg2Ali5/Plcg2+
Genetic
Background		 involves: 129 * 129S4/SvJae * C3HeB/FeJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ightm1.1Twin mutation (0 available); any Igh mutation (47 available)
Plcg2Ali5 mutation (0 available); any Plcg2 mutation (73 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:174233 )
N
• the distribution of B cell subsets in the peritoneal cavity is normal
increased B-1a cell number ( J:174233 )
• compared with Ightm1.1Twin homozygotes

hematopoietic system
increased B-1a cell number ( J:174233 )
• compared with Ightm1.1Twin homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory