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Phenotypes Associated with This Genotype
Genotype
MGI:5086218
Allelic
Composition
Amelxtm1Kul/Amelxtm1Kul
Tg(AMELX-LRAP)9Gibs/0
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amelxtm1Kul mutation (2 available); any Amelx mutation (25 available)
Tg(AMELX-LRAP)9Gibs mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• molar enamel surface has a rough appearance
• hypoplastic enamel lacks normal prism structure
• enamel thickness is 10-20 um in contrast to 100 um observed in wild-type mice

growth/size/body
• molar enamel surface has a rough appearance
• hypoplastic enamel lacks normal prism structure
• enamel thickness is 10-20 um in contrast to 100 um observed in wild-type mice

skeleton
• molar enamel surface has a rough appearance
• hypoplastic enamel lacks normal prism structure
• enamel thickness is 10-20 um in contrast to 100 um observed in wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory