Phenotypes Associated with This Genotype

Genotype
MGI:5085338

• Allelic Composition: Atad1^tm1Vdaw/Atad1^tm1Vdaw; Tg(Camk2a-cre)2Gsc/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:173768 )

N • mice exhibit normal anxiety-related behavior

abnormal short-term spatial reference memory ( J:173768 )

• mice exhibit deficits in short-term memory compared with wild-type mice

abnormal spatial working memory ( J:173768 )

• in an open field test, mice exhibit increased peripheral activity compared with wild-type mice

• in a Y-maze, mice exhibit reduced spontaneous alternation compared with wild-type mice

• in a T-maze, mice spend less time in the novel arm than wild-type mice

• mice exhibit impaired place preference for a sweet milk reward compared with wild-type mice

seizures ( J:173768 )

nervous system

seizures ( J:173768 )