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Phenotypes Associated with This Genotype
Genotype
MGI:5056450
Allelic
Composition
Tg(SOD1*)125Dbo/?
Genetic
Background
involves: C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(SOD1*)125Dbo mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice develop hindlimb paralysis by 8-12 months of age

nervous system
• inclusion bodies are detected in spinal cord and brainstem
• inclusions are present at low levels in cerebral cortex and cerebellum

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
amyotrophic lateral sclerosis type 1 DOID:0060193 OMIM:105400
J:86421


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory