About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5056352
Allelic
Composition
Cd1d1tm2Aben/Cd1d1tm2Aben
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd1d1tm2Aben mutation (1 available); any Cd1d1 mutation (36 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice exhibit a reduction of Valpha14 NKT cells in the thymus and peripheral tissues such as spleen and liver due to failure of positive selection compared with wild-type mice
• thymocytes and peritoneal macrophages exhibit impaired antigen presentation of alphaGalCer compared with wild-type cells

hematopoietic system
• mice exhibit a reduction of Valpha14 NKT cells in the thymus and peripheral tissues such as spleen and liver due to failure of positive selection compared with wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory