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Phenotypes Associated with This Genotype
Genotype
MGI:5052326
Allelic
Composition		 Pdcd10tm1Kwhi/Pdcd10tm1Kwhi
Tg(Tek-cre)1Ywa/?
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdcd10tm1Kwhi mutation (0 available); any Pdcd10 mutation (18 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:173947 )
• death due to venous rupture by E13.5

cardiovascular system
cardiovascular system phenotype ( J:173947 )
N
• open branchial arch arteries and developed circulatory system at E9.5
abnormal cardinal vein morphology ( J:173947 )
• progressive enlargement of the cardinal vein until E11.5
• death due to venous rupture by E13.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory