About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5052308
Allelic
Composition
Tg(HD82Gln)81Gschi/0
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(HD82Gln)81Gschi mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• reduced lifespan compared to wild-type controls

nervous system
• ubiquitin positive aggregates in the striatum

behavior/neurological
• reduced latency to fall and an increased number of falls in a rotarod assay from 14 weeks of age

growth/size/body
• fail to gain weight after 16 weeks of age
• fail to gain weight after 16 weeks of age

Mouse Models of Human Disease
OMIM ID Ref(s)
Huntington Disease; HD 143100 J:172874


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/20/2016
MGI 6.05
The Jackson Laboratory