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Phenotypes Associated with This Genotype
Genotype
MGI:5052120
Allelic
Composition
Tg(Eno2-PSEN2*)1480Ykk/0
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• impaired performance in a water maze test at 12 months of age compared to aged matched controls
• slight reduction in swimming speed

nervous system
• increase in amyloid beta 42 levels compared to age matched controls

homeostasis/metabolism
• increase in amyloid beta 42 levels compared to age matched controls

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Alzheimer's disease DOID:10652 OMIM:104300
OMIM:502500
OMIM:604154
OMIM:608907
J:76934


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory