Mouse Genome Informatics
tg
    Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
involves: 129S4/SvJae * C57BL/6 * SJL
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• impaired survival compared to wild-type mice
• survive longer than transgenic mice that are also Apoa4 null

nervous system

homeostasis/metabolism

Mouse Models of Human Disease
OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:169682