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Phenotypes Associated with This Genotype
Genotype
MGI:5051941
Allelic
Composition
Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/?
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• impaired survival compared to wild-type mice
• survive longer than transgenic mice that are also Apoa4 null

nervous system

homeostasis/metabolism

Mouse Models of Human Disease
OMIM ID Ref(s)
Alzheimer Disease; AD 104300 J:169682


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/16/2017
MGI 6.07
The Jackson Laboratory