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Phenotypes Associated with This Genotype
Genotype
MGI:5050827
Allelic
Composition
ax/ax
Genetic
Background
B6.Cg-ax
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ax mutation (0 available); any a mutation (468 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• histological analyses reveal abnormal embryos are first evident at E4.5
• between E7.5 and E8.5 only small disorganized clumps of tissue remain

embryo
• blastocysts implant and develop to varying degrees some with trophoblast giant cells and primitive endoderm layer but all growth is retarded

growth/size/body
• blastocysts implant and develop to varying degrees some with trophoblast giant cells and primitive endoderm layer but all growth is retarded


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory