Phenotypes for Porcn Tg(Prrx1-cre)1Cjt MGI:5049888 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Porcn^tm1.1Lcm/Y Tg(Prrx1-cre)1Cjt/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Porcn^tm1.1Lcm mutation (0 available); any Porcn mutation (18 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Tissue-specific Porcn^tm1.1Lcm deletion phenotypes include skeletal defects and skin abnormalities

limbs/digits/tail

oligodactyly ( J:173672 )

• mice exhibit loss of distal digits compared with wild-type mice

• however, all individual skeletal elements are preserved

short limbs ( J:173672 )

• at E17.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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