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Phenotypes Associated with This Genotype
Genotype
MGI:5014261
Allelic
Composition
Leprtm1.1Chua/Lepr+
Tg(Gh1-cre)bKnmn/0
Genetic
Background
involves: 129 * C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Leprtm1.1Chua mutation (0 available); any Lepr mutation (85 available)
Tg(Gh1-cre)bKnmn mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• in F1 generation males, a significant decrease in growth hormone-positive somatrophs is observed

nervous system
• in F1 generation males, a significant decrease in growth hormone-positive somatrophs is observed

reproductive system
N
• mice are fertile


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory