Analysis Tools
reproductive system
 N |
• oocyte numbers are normal
|
azoospermia
(
J:173089
)
 |
• male mice lack post-meiotic cells
|
|
• oocytes contain fewer chiasmata than wild-type cells
|
|
|
• in female germ cells, autosomal synaptonemal-complex formation is never completed unlike in wild-type cells
• pseudo-sex-body-like formation is impaired compared to in wild-type cells
• oocytes contain fewer chiasmata than in wild-type cells
• however, oocytes exhibit normal nuclear envelop breakdown
|
|
|
• chromosomes fail to align along abnormally long meiosis I spindle unlike in wild-type cells
|
|
|
• in male germ cells, autosomal synaptonemal-complex formation is never completed unlike in wild-type cells
• sex-body formation is impaired compared to in wild-type cells
|
|
• autosomal synaptonemal-complex formation in spermatocytes and oocytes is never completed unlike in wild-type cells
|
|
|
• spermatocytes are eliminated at a stage equivalent to mid-pachytene unlike in wild-type mice
• spermatocytes are eliminated in stage-IV tubules unlike in wild-type mice
|
|
|
• spermatocytes are eliminated at a stage equivalent to mid-pachytene unlike in wild-type mice
• spermatocytes are eliminated in stage-IV tubules unlike in wild-type mice
|
cellular
azoospermia
(
J:173089
)
|
|
• male mice lack post-meiotic cells
|
|
• oocytes contain fewer chiasmata than wild-type cells
|
|
|
• in female germ cells, autosomal synaptonemal-complex formation is never completed unlike in wild-type cells
• pseudo-sex-body-like formation is impaired compared to in wild-type cells
• oocytes contain fewer chiasmata than in wild-type cells
• however, oocytes exhibit normal nuclear envelop breakdown
|
|
|
• chromosomes fail to align along abnormally long meiosis I spindle unlike in wild-type cells
|
|
|
• in male germ cells, autosomal synaptonemal-complex formation is never completed unlike in wild-type cells
• sex-body formation is impaired compared to in wild-type cells
|
|
• autosomal synaptonemal-complex formation in spermatocytes and oocytes is never completed unlike in wild-type cells
|
|
|
• spermatocytes are eliminated at a stage equivalent to mid-pachytene unlike in wild-type mice
• spermatocytes are eliminated in stage-IV tubules unlike in wild-type mice
|
|
• spermatocytes and oocytes exhibit reduced steady-state numbers of single-stranded double-strand break repair (DSB) ends compared to wild-type cells
|
homeostasis/metabolism
|
• spermatocytes and oocytes exhibit reduced steady-state numbers of single-stranded double-strand break repair (DSB) ends compared to wild-type cells
|
