About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5008416
Allelic
Composition		 Itgb8tm1Lfr/Itgb8tm1Lfr
Genetic
Background		 involves: 129/Sv * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb8tm1Lfr mutation (1 available); any Itgb8 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal brain vasculature morphology ( J:136106 )
• in newborn mice, brain vessels are enlarged and hyperplastic compared to in control mice
enlarged brain ventricles ( J:136106 )
• enlarged ventricles

cardiovascular system
abnormal brain vasculature morphology ( J:136106 )
• in newborn mice, brain vessels are enlarged and hyperplastic compared to in control mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory