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Phenotypes Associated with This Genotype
Genotype
MGI:5008169
Allelic
Composition		 Cd83anu/Cd83anu
Genetic
Background		 involves: C57BL/6JAnu * CBA/CaJAnu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd83anu mutation (4 available); any Cd83 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased CD4-positive, alpha-beta T cell number ( J:104190 )
• in the peripheral blood or thymus
abnormal dendritic cell morphology ( J:104190 )
• dendritic cells and B cells exhibit decreased cell surface expression of MHCII and CD86
abnormal B cell morphology ( J:104190 )
• dendritic cells and B cells exhibit decreased cell surface expression of MHCII and CD86

hematopoietic system
decreased CD4-positive, alpha-beta T cell number ( J:104190 )
• in the peripheral blood or thymus
abnormal dendritic cell morphology ( J:104190 )
• dendritic cells and B cells exhibit decreased cell surface expression of MHCII and CD86
abnormal B cell morphology ( J:104190 )
• dendritic cells and B cells exhibit decreased cell surface expression of MHCII and CD86

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory