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Phenotypes Associated with This Genotype
Genotype
MGI:5007926
Allelic
Composition
Mefvtm3.1(MEFV)Chae/Mefvtm3.1(MEFV)Chae
Genetic
Background
B6.129S6-Mefvtm3.1(MEFV)Chae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mefvtm3.1(MEFV)Chae mutation (0 available); any Mefv mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice exhibit increased CD11b+ cells compared with wild-type mice but not as much as in Mefvtm5.1(MEFV)Chae
• increased inflammatory phenotypes are less severe than in Mefvtm5.1(MEFV)Chae homozygotes
• after 4 to 8 weeks
• after 4 to 8 weeks

growth/size/body
• after 4 to 8 weeks
• after 4 to 8 weeks

integument
• after 4 to 8 weeks

skeleton
• after 4 to 8 weeks

hematopoietic system
• mice exhibit increased CD11b+ cells compared with wild-type mice but not as much as in Mefvtm5.1(MEFV)Chae

Mouse Models of Human Disease
OMIM ID Ref(s)
Familial Mediterranean Fever; FMF 249100 J:172117


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory