About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5006985
Allelic
Composition
Tg(Mov1/Tyr)OVE876BPay/Tg(Mov1/Tyr)OVE876BPay
Genetic
Background
FVB/N-Tg(Mov1/Tyr)OVE876BPay
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• females are hyperactive but do not develop perseverative circling
• pups exhibit a shift in separation-induced ultrasonic vocalization pattern, with female pups exhibiting an approximate 2 day shift in the ultrasonic vocalization development curve, such that females do not persistently decrease their vocalizations from peak levels until P10 compared to P8 in wild-type females
• young females are more likely to have a seizure when subjected to a loud sound stimulus compared to wild-type mice, however no spontaneous seizure activity is seen

integument
• females exhibit a salt-and-pepper pigmentation pattern

nervous system
• young females are more likely to have a seizure when subjected to a loud sound stimulus compared to wild-type mice, however no spontaneous seizure activity is seen
• across a range of 17-45 days of age, females exhibit a prepulse inhibition deficit indicating impaired sensorimotor gating
• across a range of 17-45 days of age, females exhibit a prepulse inhibition deficit but no difference in acoustic startle response

pigmentation
• females exhibit a salt-and-pepper pigmentation pattern

Mouse Models of Human Disease
OMIM ID Ref(s)
Autism 209850 J:167614


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory