Mouse Genome Informatics
cx
    Tg(Hmgcr-PSEN1*M146L)#Lpr/0
Tg(PDGFB-APPSwDutLon)46Lpr/0

involves: C57BL/6 * CBA
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• plaques are seen at 6 months of age
• as soon as detectable, a large number of deposits have a fibrillar conformation

homeostasis/metabolism
• plaques are seen at 6 months of age
• as soon as detectable, a large number of deposits have a fibrillar conformation

Mouse Models of Human Disease
OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:86694