Mouse Genome Informatics
cx
     Tg(Hmgcr-PSEN1*M146L)#Lpr/0
Tg(Thy1-APPLon)2Vln/0
involves: C57BL/6 * CBA * FVB/N
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
amyloid beta deposits ( J:86694 )
• plaques are seen at 6 months of age
• as soon as detectable, a large number of deposits have a fibrillar conformation

homeostasis/metabolism
amyloid beta deposits ( J:86694 )
• plaques are seen at 6 months of age
• as soon as detectable, a large number of deposits have a fibrillar conformation

Mouse Models of Human Disease
 OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:86694