Phenotypes Associated with This Genotype

Genotype
MGI:5000480

• Allelic Composition: Trp53^tm1Brn/Trp53⁺; Tg(MMTV-cre)#Tfln/0
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased mammary gland tumor incidence ( J:170898 )

• 92% of mice have mammary tumors

• many mice have tumors in more than one gland

• mammary tumors are either spindle/epithelial-mesenchymal transition or poorly differentiated adenocarcinoma

increased mammary adenocarcinoma incidence ( J:170898 )

endocrine/exocrine glands

increased mammary gland tumor incidence ( J:170898 )

• 92% of mice have mammary tumors

• many mice have tumors in more than one gland

• mammary tumors are either spindle/epithelial-mesenchymal transition or poorly differentiated adenocarcinoma

increased mammary adenocarcinoma incidence ( J:170898 )

integument

increased mammary gland tumor incidence ( J:170898 )

• 92% of mice have mammary tumors

• many mice have tumors in more than one gland

• mammary tumors are either spindle/epithelial-mesenchymal transition or poorly differentiated adenocarcinoma

increased mammary adenocarcinoma incidence ( J:170898 )