Phenotypes Associated with This Genotype

Genotype
MGI:5000478

• Allelic Composition: Gt(ROSA)26Sor^{tm1(Pik3ca*H1047R)Egan}/Gt(ROSA)26Sor⁺; Trp53^tm1Brn/Trp53^tm1Brn; Tg(MMTV-cre)#Tfln/0
• Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:170898 )

• most die early with lymphoma/thymoma

neoplasm

increased mammary gland tumor incidence ( J:170898 )

• some mice have small mammary tumors

increased lymphoma incidence ( J:170898 )

increased T cell derived lymphoma incidence ( J:170898 )

endocrine/exocrine glands

increased T cell derived lymphoma incidence ( J:170898 )

increased mammary gland tumor incidence ( J:170898 )

• some mice have small mammary tumors

integument

increased mammary gland tumor incidence ( J:170898 )

• some mice have small mammary tumors

immune system

increased T cell derived lymphoma incidence ( J:170898 )

hematopoietic system

increased T cell derived lymphoma incidence ( J:170898 )