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Phenotypes Associated with This Genotype
Genotype
MGI:4950699
Allelic
Composition
Hdac2tm1.1Eem/Hdac2tm1.1Eem
Pou5f1tm2Jae/?
Genetic
Background
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hdac2tm1.1Eem mutation (0 available); any Hdac2 mutation (38 available)
Pou5f1tm2Jae mutation (1 available); any Pou5f1 mutation (82 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mouse embryonic fibroblasts transduced with a cre-expressing adenovirus and a Mir302/367-expressing virus form Pou5f1-GFP+ produce viable induced pluripotent stem cells (iPSCs) unlike wild-type cells in the absence of valproic acid


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory