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Phenotypes Associated with This Genotype
Genotype
MGI:4950568
Allelic
Composition
Prpf31tm1.1Bha/Prpf31+
Genetic
Background
involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prpf31tm1.1Bha mutation (0 available); any Prpf31 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• loss of the basal infoldings and accumulation of amorphous deposits between the RPE and Bruch's membrane are seen at 12 months of age (J:171561)
• loss of the basal infoldings and accumulation of amorphous deposits between the RPE and Bruch's membrane are seen at 12 months of age (J:171561)
• late onset degeneration of the retinal pigment epithelium (J:171561)
• late onset degeneration of the retinal pigment epithelium (J:171561)

pigmentation
• loss of the basal infoldings and accumulation of amorphous deposits between the RPE and Bruch's membrane are seen at 12 months of age (J:171561)
• loss of the basal infoldings and accumulation of amorphous deposits between the RPE and Bruch's membrane are seen at 12 months of age (J:171561)

Mouse Models of Human Disease
OMIM ID Ref(s)
Retinitis Pigmentosa 11; RP11 600138 J:171561


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory