About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4950285
Allelic
Composition		 Ccl2tm1Rol/Ccl2tm1Rol
Tg(Ccr2-GFP)8Pam/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccl2tm1Rol mutation (2 available); any Ccl2 mutation (25 available)
Tg(Ccr2-GFP)8Pam mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal leukocyte migration ( J:171379 )
• monocytes from LPS-treated mice fail to enter the lumen of the blood vessel unlike in wild-type mice

cellular
abnormal leukocyte migration ( J:171379 )
• monocytes from LPS-treated mice fail to enter the lumen of the blood vessel unlike in wild-type mice

hematopoietic system
abnormal leukocyte migration ( J:171379 )
• monocytes from LPS-treated mice fail to enter the lumen of the blood vessel unlike in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory