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Phenotypes Associated with This Genotype
Genotype
MGI:4949922
Allelic
Composition		 Ccn2tm1.1Alea/Ccn2tm1.1Alea
Tg(Col1a2-cre/ERT,-ALPP)7Cpd/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccn2tm1.1Alea mutation (1 available); any Ccn2 mutation (28 available)
Tg(Col1a2-cre/ERT,-ALPP)7Cpd mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal skin physiology ( J:171300 )
• bleomycin-treated mice do not exhibit increased dermal thickness and collagen production unlike in similarly treated wild-type mice

homeostasis/metabolism
decreased physiological sensitivity to xenobiotic ( J:171300 )
• bleomycin-treated mice do not exhibit increased dermal thickness and collagen production unlike in similarly treated wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory