Mouse Genome Informatics
hm
    Agpsbs2/Agpsbs2
STOCK Agpsbs2/J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• some prenatal or perinatal lethality

reproductive system
• mice exhibit abnormal seminiferous tubules with multinucleate cells within the lumen compared with wild-type mice (J:171265)
(J:171265)
• mature spermatozoa or elongating spermatids are absent unlike in wild-type mice (J:171265)
(J:156373)
(J:171265)

vision/eye
• mice exhibit bladder cells and liquefied lens material within the cortex and morganian globules at the posterior poles unlike in wild-type mice
• fiber cells in the bow region are smaller in size mice and detached from the epithelium compared to in wild-type mice

homeostasis/metabolism
• mice exhibit reduced brain phosphatidylethanolamine (PE), ether-phosphatidyl ethanolamine (ePE), and ether-phosphatidyl choline (ePC) levels compared with wild-type mice
• however, levels of phosphatidylcholine (PC) are normal

endocrine/exocrine glands
• mice exhibit abnormal seminiferous tubules with multinucleate cells within the lumen compared with wild-type mice (J:171265)
(J:171265)

Mouse Models of Human Disease
OMIM IDRef(s)
Rhizomelic Chondrodysplasia Punctata, Type 3; RCDP3 600121 J:171265