Phenotypes Associated with This Genotype

Genotype
MGI:4948114

• Allelic Composition: Itga8^tm1.1Rdav/Itga8^tm1.1Rdav; Tg(Camk2a-cre)#Szi/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

impaired synaptic plasticity ( J:170959 )

• N-methyl-D-aspartate receptor-dependent long term potentiation is lower than in wild-type mice

reduced long-term potentiation ( J:170959 )

• N-methyl-D-aspartate receptor-dependent long term potentiation is lower than in wild-type mice

behavior/neurological

behavior/neurological phenotype ( J:170959 )

N • mice exhibit normal motor learning, habituation, anxiety and hippocampal-dependent spatial learning, and memory