Phenotypes Associated with This Genotype

Genotype
MGI:4943552

• Allelic Composition: Lrp1^tm2Her/Lrp1^tm2Her
• Genetic Background: involves: 129S7/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

liver/biliary system

abnormal liver physiology ( J:76281 )

• impaired ability to clear ¹²⁵I-labeled alpha2-macroglobulin from the plasma after adenoviral cre injection into the liver

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:67929 )

N • unlike in double mutant mice that are also null for Ldlr , adenoviral cre infection does not alter circulating apolipoprotein levels or the plasma cholesterol profile