Phenotypes for Ptpn11 Tg(Pax6-cre,GFP)1Pgr MGI:4943280 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ptpn11^tm1Gsf/Ptpn11^tm1Gsf Tg(Pax6-cre,GFP)1Pgr/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpn11^tm1Gsf mutation (0 available); any Ptpn11 mutation (44 available)
Tg(Pax6-cre,GFP)1Pgr mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

abnormal lacrimal gland development ( J:130571 )

• at E14.5 and P0, lacrimal gland development is disrupted compared to in wild-type mice

absent lacrimal glands ( J:130571 )

vision/eye

abnormal lacrimal gland development ( J:130571 )

• at E14.5 and P0, lacrimal gland development is disrupted compared to in wild-type mice

absent lacrimal glands ( J:130571 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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