About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4942396
Allelic
Composition
Tlr2tm1Aki/Tlr2tm1Aki
Genetic
Background
NOD.129P2-Tlr2tm1Aki
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tlr2tm1Aki mutation (4 available); any Tlr2 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• significantly reduced susceptibility to type 1 diabetes
• 38% are diabetic at 45 weeks as compared to 74% of controls

endocrine/exocrine glands
• reduced insulitis relative to controls

immune system
• reduced insulitis relative to controls

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Diabetes Mellitus, Insulin-Dependent; IDDM 222100 J:124334


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory