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Phenotypes Associated with This Genotype
Genotype
MGI:4942389
Allelic
Composition		 Apoetm1Unc/Apoetm1Unc
Cd44tm1Mak/Cd44+
Genetic
Background		 B6.129P2-Cd44tm1Mak Apoetm1Unc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoetm1Unc mutation (34 available); any Apoe mutation (163 available)
Cd44tm1Mak mutation (1 available); any Cd44 mutation (73 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased susceptibility to atherosclerosis ( J:72315 )
• reduced lesion area in the thoracic abdominal aorta
• normal plasma cholesterol levels

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory