Phenotypes for Apoe Cd44 MGI:4942387 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Apoe^tm1Unc/Apoe^tm1Unc Cd44^tm1Mak/Cd44^tm1Mak
Genetic Background	B6.129P2-Cd44^tm1Mak Apoe^tm1Unc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoe^tm1Unc mutation (35 available); any Apoe mutation (164 available)
Cd44^tm1Mak mutation (1 available); any Cd44 mutation (74 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

decreased susceptibility to atherosclerosis ( J:72315 )

• reduced lesion area in the aortic root and thoracic abdominal aorta in a gene dosage-dependent manner

• normal plasma cholesterol levels

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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