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Phenotypes Associated with This Genotype
Genotype
MGI:4941902
Allelic
Composition		 Cd44tm1Hbg/Cd44tm1Hbg
Genetic
Background		 B6.129-Cd44tm1Hbg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd44tm1Hbg mutation (4 available); any Cd44 mutation (74 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased mast cell number ( J:146846 )
• decreased mast cell numbers in the peritoneal cavities and ear tissues
• decreased mast cell numbers in the bone marrow-derived mast cells co-cultured with fibroblasts starting at day 4
decreased mast cell histamine storage ( J:146846 )
• decreased histamine content in the peritoneal cavities and ear tissues

immune system
decreased mast cell number ( J:146846 )
• decreased mast cell numbers in the peritoneal cavities and ear tissues
• decreased mast cell numbers in the bone marrow-derived mast cells co-cultured with fibroblasts starting at day 4
decreased mast cell histamine storage ( J:146846 )
• decreased histamine content in the peritoneal cavities and ear tissues

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory