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Phenotypes Associated with This Genotype
Genotype
MGI:4941348
Allelic
Composition
Crebbptm1.2Ltz/Crebbptm1.2Ltz
Tg(Camk2a-cre)T29-1Stl/0
Genetic
Background
involves: 129P2/OlaHsd * BALB/c * C57BL * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crebbptm1.2Ltz mutation (0 available); any Crebbp mutation (23 available)
Tg(Camk2a-cre)T29-1Stl mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice exhibit normal anxiety levels, fear conditioning, and spatial navigation (J:168984)
• mice exhibit normal anxiety levels, fear conditioning, and spatial navigation (J:168984)
• after 3 consecutive days in the same arena, mice exhibit slightly less locomotor habituation compared with wild-type mice (J:168984)
• after 3 consecutive days in the same arena, mice exhibit slightly less locomotor habituation compared with wild-type mice (J:168984)
• mice exhibit impaired long term recognition memory compared with wild-type mice (J:168984)
• mice exhibit impaired long term recognition memory compared with wild-type mice (J:168984)

nervous system
N
• neuronal viability is normal (J:168984)
• neuronal viability is normal (J:168984)

Mouse Models of Human Disease
OMIM ID Ref(s)
Rubinstein-Taybi Syndrome 1; RSTS1 180849 J:168984


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory