Phenotypes Associated with This Genotype

Genotype
MGI:4941218

• Allelic Composition: Bmp4^tm1Jfm/Bmp4^tm1Jfm; Tg(Mef2c-cre)2Blk/0
• Genetic Background: involves: 129S4/SvJaeSor

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal cardiac outflow tract development ( J:169047 )

• defect in outflow tract remodeling at E12.5 due to a deficiency in proximal outflow tract mesenchyme

abnormal truncus arteriosus septation ( J:169047 )

• at E14.5 and E18.5, a deficiency in the separation of the proximal outflow tract is seen

abnormal heart and great artery attachment ( J:169047 )

• at E14.5 and E18.5, the alignment of the aorta and pulmonary trunk is abnormal