Phenotypes for Hand2 Tg(Tbx1-cre)#Dsr MGI:4940094 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hand2^tm1Dsr/Hand2^tm2.1Dsr Tg(Tbx1-cre)#Dsr/0
Genetic Background	involves: 129 * 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hand2^tm1Dsr mutation (0 available); any Hand2 mutation (14 available)
Hand2^tm2.1Dsr mutation (0 available); any Hand2 mutation (14 available)
Tg(Tbx1-cre)#Dsr mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:169213 )

• mice die at E15.5

cardiovascular system

abnormal cardiac outflow tract development ( J:169213 )

• shortened at E10.5 and E13.5

decreased heart right ventricle size ( J:169213 )

• at E13.5, but not at E10.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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