Phenotypes for Slc17a6 Tg(PLAT-cre)116Sdu MGI:4887827 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Slc17a6^tm1Kldr/Slc17a6^tm1Kldr Tg(PLAT-cre)116Sdu/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc17a6^tm1Kldr mutation (1 available); any Slc17a6 mutation (60 available)
Tg(PLAT-cre)116Sdu mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

excessive scratching ( J:167752 )

increased thermal nociceptive threshold ( J:167752 )

• mice display decreased responsiveness to radiant heat

integument

increased pruritus ( J:167752 )

• mice display a chronic itch behavior (display frequent scratching episodes)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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