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Phenotypes Associated with This Genotype
Genotype
MGI:4881702
Allelic
Composition
\Sema4ctm1Matl/\Sema4c+
\Sema4gtm1Kik/\Sema4gtm1Kik
Genetic
Background
B6.Cg-Sema4ctm1Matl Sema4gtm1Kik
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sema4ctm1Matl mutation (0 available); any Sema4c mutation (36 available)
Sema4gtm1Kik mutation (0 available); any Sema4g mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• 50% of mice exhibit gaps in the granule layer of lobule II unlike wild-type mice
• 60% of mice exhibit ectopic granule cells in the molecular layer at subpilial positions unlike wild-type mice
• 69% of mice exhibit rostral lobules VIII and IX fusion unlike in wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory