Phenotypes for Grm6 MGI:4880735 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Grm6^nob3/Grm6^nob4
Genetic Background	involves: C57BL/6J * C57BL/10 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grm6^nob3 mutation (1 available); any Grm6 mutation (52 available)
Grm6^nob4 mutation (0 available); any Grm6 mutation (52 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal eye physiology ( J:152828 )

• spatial frequency threshold is lower than in wild-type mice

• the spatial frequency cutoffs are lower than in wild-type mice

• however, peak contrast sensitivity is normal

abnormal cone electrophysiology ( J:152828 )

• photopic b-waves are absent

• however, a-waves are normal

abnormal rod electrophysiology ( J:152828 )

• scotopic b-waves are absent

• mice lack a scotopic threshold response unlike wild-type mice

• however, a-waves are normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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