Analysis Tools
growth/size/body
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• detected in females by 5 weeks of age
• females are about 11% heavier than control littermates at 20 weeks of age
• males are about 7% heavier than control littermates at 20 weeks of age
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• increased weight gain on a high fat diet compared to diet matched controls
• increase in fat mass on a high fat diet is more pronounced in females
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behavior/neurological
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• increase in food intake on both standard and high fat diets
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adipose tissue
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• increase in fat mass in both males and females
• increase is less than in homozygous mice
• increase in fat mass on a high fat diet is more pronounced in females
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• increase in epigonadal and abdominal white adipose tissues
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homeostasis/metabolism
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• increased weight gain on a high fat diet compared to diet matched controls
• increase in fat mass on a high fat diet is more pronounced in females
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• in females at 20 weeks of age
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• in females at 20 weeks of age
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• in females at 20 weeks of age
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• in females at 20 weeks of age
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• in males at 20 weeks of age when corrected for fat mass
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• in females on a high fat diet and in males on a standard diet
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