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Phenotypes Associated with This Genotype
Genotype
MGI:4867887
Allelic
Composition
Itm2btm1.1Ldad/Itm2btm1.1Ldad
Genetic
Background
involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itm2btm1.1Ldad mutation (0 available); any Itm2b mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice spend the same time exploring a novel and familiar object introduced 24 hours prior unlike wild-type mice
• mice exhibit impaired spatial working memory compared with wild-type mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
cerebral amyloid angiopathy DOID:9246 OMIM:105150
OMIM:117300
OMIM:176500
OMIM:605714
J:166696


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/15/2017
MGI 6.10
The Jackson Laboratory