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Phenotypes Associated with This Genotype
Genotype
MGI:4867046
Allelic
Composition		 Cd74tm1Eae/Cd74tm1Eae
Genetic
Background		 B6.129S2-Cd74tm1Eae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd74tm1Eae mutation (0 available); any Cd74 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
arrested B cell differentiation ( J:112084 )
• arrest at the immature B cell stage
abnormal lymph node cell ratio ( J:112084 )
• striking decrease in the proportion of B cells in the lymph nodes

hematopoietic system
arrested B cell differentiation ( J:112084 )
• arrest at the immature B cell stage

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory