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Phenotypes Associated with This Genotype
Genotype
MGI:4849372
Allelic
Composition
f/f
KitW/Kit+
Genetic
Background
FL/1Re-KitW/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
f mutation (4 available); any f mutation (4 available)
KitW mutation (10 available); any Kit mutation (179 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• although slightly reduced in body weight relative to controls this is less severe than in flexed-tail homozygotes wildtype at the Kit locus

hematopoietic system
• the reduction in erythrocyte cell number at birth is less severe than in flex-tail homozygotes that are wildtype at the Kit locus and by 7 days of age the count is higher than normal and this persists
• decreased at birth, but closer to normal values than in flexed-tail homozgyotes that are wildtype at the Kit locus
• from birth onward more severe decrease in erythrocyte volume than in flexed-tail homozygotes wildtype at the Kit locus

pigmentation
• the amount of white pigmentation is greater than the sum of the white pigmentation of the distinct mutants, with females having an average of 54.7% white on the ventrum and males having an average of 59.7%

integument
• the amount of white pigmentation is greater than the sum of the white pigmentation of the distinct mutants, with females having an average of 54.7% white on the ventrum and males having an average of 59.7%


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory