Phenotypes for Mlst8 Pten MGI:4848146 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mlst8^tm1Lex/Mlst8⁺ Pten^tm1Rps/Pten⁺
Genetic Background	involves: 129S1/Sv * 129S5/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mlst8^tm1Lex mutation (1 available); any Mlst8 mutation (22 available)
Pten^tm1Rps mutation (0 available); any Pten mutation (86 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

extended life span ( J:144810 )

• double mutants live longer than single heterozygous Pten mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/20/2026 MGI 6.24