Phenotypes Associated with This Genotype

Genotype
MGI:4844107

• Allelic Composition: Del(11Stat5a-Stat5b)1Mam/Del(11Stat5a-Stat5b)1Mam
• Genetic Background: involves: 129S6/SvEvTac * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:138904 )

• die within hours after birth

hematopoietic system

hypochromic microcytic anemia ( J:138904 )

• microcytic, hypochromic anemia

decreased hematocrit ( J:138904 )

• severely anemic with hematocrits of approximately 1.6 in neonates, compared with 4.7 (47%) in controls

decreased mean corpuscular hemoglobin ( J:138904 )

• reduced red cell size (mean corpuscular volume) and hemoglobin content